It is a night on which Jose Mourinho set out not lose as Manchester United hope to keep touch with the main pack. The impact an outcome could have for either is gigantic in a game to rival El Clasico for its power.
A crotch issue implies Adam Lallana is set to miss out a major opportunity for Liverpool, alongside Georginio Wijnaldum after he was injured playing for the Netherlands.
Defenders Nathaniel Clyne and Dejan Lovren are back in conflict and fit-again Emre Can could make a first league begin of the season.
Manchester United’s Henrikh Mkhitaryan and defender Luke Shaw are fit for the excursion to Anfield taking after injuries.
Phil Jones is the main player sidelined in a generally completely fit squad.
Here is what the Both teams Managers Say
Manchester United manager Jose Mourinho on concerns over disrespectful chanting at the game: “In football we have some football tragedies, if you can say that, which is a big match that you lost, the mistake that some player did, this kind of thing, and you can make fun of it in a positive way.
“But the human tragedy is something much more serious. It’s the last thing somebody should use in a football pitch because they were really big tragedies, not to forget but to respect.
“I will be really sad in such a big football match if that was a negative point.”
Liverpool manager Jurgen Klopp: “Apart from the table, it’s a very important game. I know about the history, I like the special stories. The whole world will watch this game, it’s a big honour to be part of it.
“At the end, it’s up to us to perform to our best. You cannot and should not ignore the special circumstance of a game like this. You have to be ready.
“They have big quality and we have to respect this, as we do. But this is Anfield. We have to show this. We have had a few nice atmospheres but I’m open for the best atmosphere. We need everybody in a Liverpool shirt in this game.”
- A defeat for Liverpool will be the first occasion when they have lost three straight home class matches to Manchester United since January 2005.
- Manchester United have won their last four league games against Liverpool and seven of the last nine.
- That run of four defeats for Liverpool is their most exceedingly terrible since losing five sequential matches to Manchester United in March 2008.
- Liverpool have lost 67 class matches against Manchester United – more than against some other rival.
- There hasn’t been a draw between the two sides domestically since a 1-1 league stalemate at Anfield in October 2011.
- Steven Gerrard, with eight goals, is the top scorer in this fixture in the Premier League time. Wayne Rooney and Robbie Fowler both have six.
- Jose Mourinho’s men have won just once in their last four league games, yielding seven goals.
- Wayne Rooney as of now has 87 Premier League away goals, the joint-most in the opposition nearby Alan Shearer.
- Manchester United had three points more at this stage last season under Louis Van Gaal (16).
- Marcus Rashford has scored 12 goals since his entrance for Manchester United on 25 February 2016, four more than any other Manchester United player.
- Liverpool are going for a fifth win on the run which would be their best keep running since March 2015.
- Since Jurgen Klopp was designated as Liverpool manager in October 2015 they have scored a league high 73 goals and have the highest average possession figure of 58.8%.
- Liverpool have failed to keep a clean sheet in their last nine league games.
- Klopp has lost only one of his five meetings with Jose Mourinho, winning three and drawing one.
- James Milner has been involved in 21 Premier League goals since the begin of last season – nine goals and 12 assists – more than some other Liverpool player.